Descriere
Supliment alimentar cu una formulare unica de 17 ingrediente ingrediente active. È specialmente formulat pentru aiutare piele a combattere i radicali liberi pentru prevenire riduzione al colagen e mantenere piele, unghii e păr sani.

Ingrediente
Vitamina C (acid L-ascorbico), glucosamina cloridrato (glucosamina HCl), extract uscată de tè verde (40% EGCG, Camellia sinensis (L.) Kuntze), Vitamina E (alfa-tocoferolo), vitamina B3 (niacina), gluconato de zinc, ialuronato de sodiu, coenzima Q10 (ubidecarenone), beta-carotene, vitamina B6 (piridossina cloridrato), Vitamina A (retinil acetato), gluconato de rame, extract de pepe negru (95% piperine - Piper nigrum L.), luteina, astaxantina (soia), L-selenio metionina, vitamina H (biotina); agenti de carica: cellulosa microcristallina, calciu fosfato; antiagglomeranti: magneziu stearato de origine vegetală, biossido de silicio; stabilizzante: carbossimetilcellulosa sodica reticolata; agenti de rivestimento: idrossipropilmetilcellulosa, cellulosa microcristallina, acid stearico; coloranti alimentari: E101, E172.2.

Fără gluten e lactoză.
Potrivit a vegetariani e vegani.
Nu conține conservanți, zaharuri e dolcificanti artificiali.

Caracteristici nutrizionali

Valori medi	Pentru unic sticlă (50 ml)	VNR*
Vitamina C	80 mg	100%
Glucosamina	30 mg	-
Extract de tè verde	20 mg	-
Vitamina E (alfa-tocoferolo)	10 mg	83%
Vitamina B3 (niacina)	10 mg	63%
Zinc	10 mg	100%
Acid hialuronic	5 mg	-
Coenzima Q10 (ubidecarenone)	3 mg	-
Beta-carotene	2 mg	-
Vitamina B6	1,5 mg	107%
Vitamina A (RE)	1 mg	125%
Rame	1 mg	100%
Extract de pepe negru	1 mg	-
Luteina	0,5 mg	-
Astaxantina	0,5 mg	-
Selenio	0,07 mg	127%
Vitamina H (biotina)	0,05 mg	100%

*VNR: valori nutritivi de riferimento

Mod de utilizare
Si consiglia de a lua una comprimat la zi a stomaco Acoperire completă o secondo indicazione al medic pentru almeno un mese, preferibilmente pentru un periodo più lungo pentru ottenere rezultate più duraturi.

Avertismente
Nu a depăși doza zilnică recomandat. A păstra afară dalla la îndemână dei copii la de sotto dei 3 anni de vârstă. Gli suplimente nu vanno intesi come înlocuitori de una dietă variat. Consultare medic curante înainte de a lua produs în caso si stiano assumendo già altri suplimente alimentari o în caso de allergie alimentari, de aport de farmaci o se sottoposti a cure mediche. Consultare medic se si osserva una reazione indesiderata. Consultare medic în caso de stato de sarcină o alăptare înainte de a lua Aur Collagen Defence.

Păstrare
Conservare ad una temperatura inferiore a 30°C, departe dalla luce diretta al soare e dal căldură e proteggere dall'umidità. data expirării si riferisce la produs păstrat corect cu ambalaj integra.
Termen de valabilitate a ambalaj nedeschis: 24 luni

Dimensiune
Ambalaj de la 30 comprimate

Bibliografia
Baumann L: Piele ageing and its treatment. Ceai Journal of pathology 2007, 211:241- 51.
Guercio-Hauer C, Macfarlane DF, Deleo VA: Photodamage, photoaging and photoprotection of ceai piele. American family physician 1994, 50:327-32, 34.
Thiele JJ: Oxidative targets în ceai stratum corneum. A nou basis for antioxidative strategies. Piele pharmacology and applied piele physiology 2001, 14 Suppl 1:87-91.
Levine RL, Stadtman ER: Oxidative modification of proteins during ageing. Experimental gerontology 2001, 36:1495-502.
Bickers DR, Athar M: Oxidative stress în ceai pathogenesis of piele disease. Ceai Journal of investigative dermatology 2006, 126:2565-75.
Rani AJ, Mythili SV: Study pe total antioxidant status în relation to oxidative stress în type 2 diabetes mellitus. Journal of clinical and diagnostic research: JCDR 2014, 8:108-10.
Sawitzke AD, Shi H, Finco MF, Dunlop DD, Bingham CO, 3rd, Harris CL, Singer NG, Bradley JD, Argint D, Jackson CG, Lane NE, Oddis CV, Wolfe F, Lisse J, Furst DE, Reda DJ, Moskowitz RW, Williams HJ, Clegg DO: Ceai effect of glucosamine and/or chondroitin sulfate pe ceai progression of knee osteoarthritis: a report from ceai glucosamine/chondroitin arthritis intervention trial. Arthritis and rheumatism 2008, 58:3183-91.
Clegg DO, Reda DJ, Harris CL, Klein MA, O'Dell JR, Hooper MM, Bradley JD, Bingham CO, 3rd, Weisman MH, Jackson CG, Lane NE, Cush JJ, Moreland LW, Schumacher HR, Jr., Oddis CV, Wolfe F, Molitor JA, Yocum DE, Schnitzer TJ, Furst DE, Sawitzke AD, Shi H, Brandt KD, Moskowitz RW, Williams HJ: Glucosamine, chondroitin sulphate, and ceai two în combination for painful knee osteoarthritis. Ceai Nou England journal of medicine 2006, 354:795-808.
Murad H, Tabibian MP: Ceai effect of an oral supplement containing glucosamine, amino acids, minerals, and antioxidants pe cutaneousageing: a preliminary study. Ceai Journal of dermatological treatment 2001, 12:47-51.
Yuan JP, Peng J, Yin K, Wang JH: Potential health-promoting effects of astaxanthin: a high-value carotenoid mostly from microalgae. Molecular nutrition & food research 2011, 55:150-65.
Miki W: Biological functions and activities of animal carotenoids. Pur and Applied Chemistry 1991, 63 141–6.
Matsuno T: Xanthophylls as precursors of retinoids. Pur and Applied Chemistry 1991, 63: 81–8.
Lee SJ, Bai SK, Lee KS, Namkoong S, Na HJ, Ha KS, Han JA, Yim SV, Chang K, Kwon YG, Lee SK, Kim YM: Astaxanthin inhibits nitric oxide production and inflammatory gene expression by suppressing I(kappa)B kinase-dependent NF-kappa B activation. Molecules and cells 2003, 16:97-105.
Goto S, Kogure K, Abe K, Kimata Y, Kitahama K, Yamashita E, Terada H: Efficient radical trapping at ceai surface and inside ceai phospholipid membrane is responsible for highly potent antiperoxidative activity of ceai carotenoid astaxanthin. Biochimica et biophysica acta 2001, 1512:251-8.
Yamashita E: Suppression of post-UVB hyperpigmentation by topical astaxanthin from krill. Fragrance Journal 1995, 14:180–5.
Arakane K: Superior piele protection via astaxanthin. Carotenoid Science 2002, 5:21–4.
Hama S, Takahashi K, Inai Y, Shiota K, Sakamoto R, Yamada A, Tsuchiya H, Kanamura K, Yamashita E, Kogure K: Protective effects of topical application of a poorly soluble antioxidant astaxanthin liposomal formulation pe ultraviolet-induced piele damage. Journal of pharmaceutical sciences 2012, 101:2909-16.
Biswal S: Oxidative stress and astaxanthin: Ceai novel supernutrient carotenoid. International Journal of Health & Allied Sciences 2014, 3:147-53.
Cho S, Lee DH, Won CH, Kim SM, Lee S, Lee MJ, Chung JH: Differential effects of low-doză and high-doză beta-carotene supplementation pe ceai signs of photoaging and type I procollagen gene expression în human piele în vivo. Dermatology 2010, 221:160-71.
Lee J, Jiang S, Levine N, Watson RR: Carotenoid supplementation reduces erythema în human piele after simulated solar radiation exposure. Proceedings of ceai Society for Experimental Biology and Medicine Society for Experimental Biology and Medicine 2000, 223:170-4.
Kopcke W, Krutmann J: Protection from sunburn with beta-Carotene--a metaanalysis. Photochemistry and photobiology 2008, 84:284-8.
Littarru GP, Tiano L: Bioenergetic and antioxidant properties of coenzyme Q10: recent developments. Molecular biotechnology 2007, 37:31-7.
Inui M, Ooe M, Fujii K, Matsunaka H, Yoshida M, Ichihashi M: Mechanisms of inhibitory effects of CoQ10 pe UVB-induced wrinkle formation în vitro and în vivo. BioFactors 2008, 32:237-43.
Zhang M, Dang L, Guo F, Wang X, Zhao W, Zhao R: Coenzyme Q(10) enhances dermal elastin expression, inhibits -1alpha production and melanin synthesis în vitro. International journal of cosmetic science 2012, 34:273-9.
Muta-Takada K, Terada T, Yamanishi H, Ashida Y, Inomata S, Nishiyama T, Amano S: Coenzyme Q10 protects against oxidative stress-induced cell death and enhances ceai synthesis of basement membrane components în dermal and epidermal cells. BioFactors 2009, 35:435-41.
Forester SC, Lambert JD: Ceai role of antioxidant versus pro-oxidant effects of green tea polyphenols în cancer prevention. Molecular nutrition & food research 2011, 55:844-54.
Ahmed S, Anuntiyo J, Malemud CJ, Haqqi TM: Biological basis for ceai use of botanicals în osteoarthritis and rheumatoid arthritis: a review. Evidence-based complementary and alternative medicine : eCAM 2005, 2:301-8.
Lacroix S, Bouez C, Vidal S, Cenizo V, Reymermier C, Justin V, Vicanova J, Damour O: Supplementation with a complex of activ nutrients improved dermal and epidermal characteristics în piele equivalents generated from fibroblasts from young or aged donors. Biogerontology 2007, 8:97-109.
Madhan B, Krishnamoorthy G, Rao JR, Nair BU: Role of green tea polyphenols în ceai inhibition of collagenolytic activity by collagenase. International journal of biological macromolecules 2007, 41:16-22.
Katiyar SK: Piele photoprotection by green tea: antioxidant and immunomodulatory effects. Current drug targets Immune, endocrine and metabolic disorders 2003, 3:234-42.
Chiu AE, Chan JL, Kern DG, Kohler S, Rehmus WE, Kimball AB: Double-blinded, placebo-controlled trial of green tea extracts în ceai clinical and histologic appearance of photoaging piele. Dermatologic surgery: official publication for American Society for Dermatologic Surgery [et la] 2005, 31:855- 60; discussion 60.
Watanabe-Kamiyama M, Shimizu M, Kamiyama S, Taguchi Y, Sone H, Morimatsu F, Shirakawa H, Furukawa Y, Komai M: Absorption and effectiveness of orally administered low molecular weight collagen hydrolysate în rats. Journal of agricultural and food chemistry 2010, 58:835-41.
Aito-Inoue M, Lackeyram D, Fan MZ, Sato K, Mine Y: Transport of a tripeptide, Gly-Pro-Hyp, across ceai porcine intestinal brush-border membrane. Journal of peptide science: an official publication of ceai European Peptide Society 2007, 13:468-74.
Toshihide S: Clinical effects of dietary hyaluronic acid pe dry, rough piele. . Aesthetic Dermatology 2002, 12:109-20.
Kawada C, Yoshida T, Yoshida H, Matsuoka R, Sakamoto W, Odanaka W, Sato T, Yamasaki T, Kanemitsu T, Masuda Y, Urushibata O: Ingested hyaluronan moisturizes dry piele. Nutrition journal 2014, 13:70.
Roberts RL, Green J, Lewis B: Lutein and zeaxanthin în eye and piele health. Clinics în dermatology 2009, 27:195-201.
Gonzalez S, Astner S, An W, Goukassian D, Pathak MA: Dietary lutein/zeaxanthin decreases ultraviolet B-induced epidermal hyperproliferation and acute inflammation în hairless mice. Ceai Journal of investigative dermatology 2003, 121:399-405.
Lee EH, Faulhaber D, Hanson KM, Ding W, Peters S, Kodali S, Granstein RD: Dietary lutein reduces ultraviolet radiation-induced inflammation and immunosuppression. Ceai Journal of investigative dermatology 2004, 122:510-7.
Palombo P, Fabrizi G, Ruocco V, Ruocco E, Fluhr J, Roberts R, Morganti P: Beneficial long-term effects of combined oral/topical antioxidant treatment with ceai carotenoids lutein and zeaxanthin pe human piele: a double-blind, placebo-controlled study. Piele pharmacology and physiology 2007, 20:199-210.