Opis
Suplement żywność z una formulacja unica z 17 składniki składniki aktywne. È specialmente sformułowany dla aiutare skóra a combattere i radicali liberi dla prevenire riduzione z kolagen e mantenere skóra, paznokcie e włosy sani.

Składniki
Witamina C (kwas L-ascorbico), glucosamina cloridrato (glucosamina HCl), ekstrakt sucha z tè zielony (40% EGCG, Camellia sinensis (L.) Kuntze), Witamina E (alfa-tocoferolo), witamina B3 (niacina), gluconato z cynk, ialuronato z sód, coenzima Q10 (ubidecarenone), beta-carotene, witamina B6 (piridossina cloridrato), Witamina A (retinil acetato), gluconato z rame, ekstrakt z pepe czarny (95% piperine - Piper nigrum L.), luteina, astaxantina (soia), L-selenio metionina, witamina H (biotina); agenti z carica: cellulosa microcristallina, wapń fosfato; antiagglomeranti: magnez stearato roślinny, biossido z silicio; stabilizzante: carbossimetilcellulosa sodica reticolata; agenti z rivestimento: idrossipropilmetilcellulosa, cellulosa microcristallina, kwas stearico; coloranti alimentari: E101, E172.2.

Wolny od gluten e laktoza.
Odpowiedni a vegetariani e vegani.
Nie zawiera konserwanty, cukry e dolcificanti artificiali.

Cechy nutrizionali

Valori medi	Dla pojedynczy butelka (50 ml)	VNR*
Witamina C	80 mg	100%
Glucosamina	30 mg	-
Ekstrakt z tè zielony	20 mg	-
Witamina E (alfa-tocoferolo)	10 mg	83%
Witamina B3 (niacina)	10 mg	63%
Cynk	10 mg	100%
Kwas hialuronowy	5 mg	-
Coenzima Q10 (ubidecarenone)	3 mg	-
Beta-carotene	2 mg	-
Witamina B6	1,5 mg	107%
Witamina A (RE)	1 mg	125%
Rame	1 mg	100%
Ekstrakt z pepe czarny	1 mg	-
Luteina	0,5 mg	-
Astaxantina	0,5 mg	-
Selenio	0,07 mg	127%
Witamina H (biotina)	0,05 mg	100%

*VNR: valori nutritivi z riferimento

Sposób użycia
Si consiglia z przyjmować una tabletka do dzień a stomaco Pełne krycie o secondo indicazione z lekarz dla almeno un mese, preferibilmente dla un periodo più lungo dla ottenere wyniki più duraturi.

Ostrzeżenia
Nie przekraczać dawka dobowa zalecany. Przechowywać poza dalla zasięg dei dzieci do z sotto dei 3 anni z wiek. Gli suplementy nie vanno intesi come substytuty z una dieta urozmaicony. Consultare lekarz curante przed z przyjmować produkt w caso si stiano assumendo già altri suplementy alimentari o w caso z allergie alimentari, z spożycie z farmaci o se sottoposti a cure mediche. Consultare lekarz se si osserva una reazione indesiderata. Consultare lekarz w caso z stato z ciąża o karmienie piersią przed z przyjmować Złoto Collagen Defence.

Przechowywanie
Conservare ad una temperatura inferiore a 30°C, z dala dalla luce diretta z słońce e dal ciepło e proteggere dall'umidità. data ważności si riferisce do produkt przechowywany prawidłowo z opakowanie integra.
Okres trwałości a opakowanie nieotwarty: 24 miesiące

Rozmiar
Opakowanie z 30 tabletki

Bibliografia
Baumann L: Skóra ageing and its treatment. Herbata Journal of pathology 2007, 211:241- 51.
Guercio-Hauer C, Macfarlane DF, Deleo VA: Photodamage, photoaging and photoprotection of herbata skóra. American family physician 1994, 50:327-32, 34.
Thiele JJ: Oxidative targets w herbata stratum corneum. A nowy basis for antioxidative strategies. Skóra pharmacology and applied skóra physiology 2001, 14 Suppl 1:87-91.
Levine RL, Stadtman ER: Oxidative modification of proteins during ageing. Experimental gerontology 2001, 36:1495-502.
Bickers DR, Athar M: Oxidative stress w herbata pathogenesis of skóra disease. Herbata Journal of investigative dermatology 2006, 126:2565-75.
Rani AJ, Mythili SV: Study na całkowity antioxidant status w relation to oxidative stress w type 2 diabetes mellitus. Journal of clinical and diagnostic research: JCDR 2014, 8:108-10.
Sawitzke AD, Shi H, Finco MF, Dunlop DD, Bingham CO, 3rd, Harris CL, Singer NG, Bradley JD, Srebro D, Jackson CG, Lane NE, Oddis CV, Wolfe F, Lisse J, Furst DE, Reda DJ, Moskowitz RW, Williams HJ, Clegg DO: Herbata effect of glucosamine and/or chondroitin sulfate na herbata progression of knee osteoarthritis: a report from herbata glucosamine/chondroitin arthritis intervention trial. Arthritis and rheumatism 2008, 58:3183-91.
Clegg DO, Reda DJ, Harris CL, Klein MA, O'Dell JR, Hooper MM, Bradley JD, Bingham CO, 3rd, Weisman MH, Jackson CG, Lane NE, Cush JJ, Moreland LW, Schumacher HR, Jr., Oddis CV, Wolfe F, Molitor JA, Yocum DE, Schnitzer TJ, Furst DE, Sawitzke AD, Shi H, Brandt KD, Moskowitz RW, Williams HJ: Glucosamine, chondroitin sulphate, and herbata two w combination for painful knee osteoarthritis. Herbata Nowy England journal of medicine 2006, 354:795-808.
Murad H, Tabibian MP: Herbata effect of an oral supplement containing glucosamine, amino acids, minerals, and antioxidants na cutaneousageing: a preliminary study. Herbata Journal of dermatological treatment 2001, 12:47-51.
Yuan JP, Peng J, Yin K, Wang JH: Potential health-promoting effects of astaxanthin: a high-value carotenoid mostly from microalgae. Molecular nutrition & food research 2011, 55:150-65.
Miki W: Biological functions and activities of animal carotenoids. Czysty and Applied Chemistry 1991, 63 141–6.
Matsuno T: Xanthophylls as precursors of retinoids. Czysty and Applied Chemistry 1991, 63: 81–8.
Lee SJ, Bai SK, Lee KS, Namkoong S, Na HJ, Ha KS, Han JA, Yim SV, Chang K, Kwon YG, Lee SK, Kim YM: Astaxanthin inhibits nitric oxide production and inflammatory gene expression by suppressing I(kappa)B kinase-dependent NF-kappa B activation. Molecules and cells 2003, 16:97-105.
Goto S, Kogure K, Abe K, Kimata Y, Kitahama K, Yamashita E, Terada H: Efficient radical trapping at herbata surface and inside herbata phospholipid membrane is responsible for highly potent antiperoxidative activity of herbata carotenoid astaxanthin. Biochimica et biophysica acta 2001, 1512:251-8.
Yamashita E: Suppression of po-UVB hyperpigmentation by topical astaxanthin from krill. Fragrance Journal 1995, 14:180–5.
Arakane K: Superior skóra protection via astaxanthin. Carotenoid Science 2002, 5:21–4.
Hama S, Takahashi K, Inai Y, Shiota K, Sakamoto R, Yamada A, Tsuchiya H, Kanamura K, Yamashita E, Kogure K: Protective effects of topical application of a poorly soluble antioxidant astaxanthin liposomal formulation na ultraviolet-induced skóra damage. Journal of pharmaceutical sciences 2012, 101:2909-16.
Biswal S: Oxidative stress and astaxanthin: Herbata novel supernutrient carotenoid. International Journal of Health & Allied Sciences 2014, 3:147-53.
Cho S, Lee DH, Won CH, Kim SM, Lee S, Lee MJ, Chung JH: Differential effects of low-dawka and high-dawka beta-carotene supplementation na herbata signs of photoaging and type I procollagen gene expression w human skóra w vivo. Dermatology 2010, 221:160-71.
Lee J, Jiang S, Levine N, Watson RR: Carotenoid supplementation reduces erythema w human skóra after simulated solar radiation exposure. Proceedings of herbata Society for Experimental Biology and Medicine Society for Experimental Biology and Medicine 2000, 223:170-4.
Kopcke W, Krutmann J: Protection from sunburn with beta-Carotene--a metaanalysis. Photochemistry and photobiology 2008, 84:284-8.
Littarru GP, Tiano L: Bioenergetic and antioxidant properties of coenzyme Q10: recent developments. Molecular biotechnology 2007, 37:31-7.
Inui M, Ooe M, Fujii K, Matsunaka H, Yoshida M, Ichihashi M: Mechanisms of inhibitory effects of CoQ10 na UVB-induced wrinkle formation w vitro and w vivo. BioFactors 2008, 32:237-43.
Zhang M, Dang L, Guo F, Wang X, Zhao W, Zhao R: Coenzyme Q(10) enhances dermal elastin expression, inhibits -1alpha production and melanin synthesis w vitro. International journal of cosmetic science 2012, 34:273-9.
Muta-Takada K, Terada T, Yamanishi H, Ashida Y, Inomata S, Nishiyama T, Amano S: Coenzyme Q10 protects against oxidative stress-induced cell death and enhances herbata synthesis of basement membrane components w dermal and epidermal cells. BioFactors 2009, 35:435-41.
Forester SC, Lambert JD: Herbata role of antioxidant versus pro-oxidant effects of green tea polyphenols w cancer prevention. Molecular nutrition & food research 2011, 55:844-54.
Ahmed S, Anuntiyo J, Malemud CJ, Haqqi TM: Biological basis for herbata use of botanicals w osteoarthritis and rheumatoid arthritis: a review. Evidence-based complementary and alternative medicine : eCAM 2005, 2:301-8.
Lacroix S, Bouez C, Vidal S, Cenizo V, Reymermier C, Justin V, Vicanova J, Damour O: Supplementation with a kompleks of aktywny nutrients improved dermal and epidermal characteristics w skóra equivalents generated from fibroblasts from young or aged donors. Biogerontology 2007, 8:97-109.
Madhan B, Krishnamoorthy G, Rao JR, Nair BU: Role of green tea polyphenols w herbata inhibition of collagenolytic activity by collagenase. International journal of biological macromolecules 2007, 41:16-22.
Katiyar SK: Skóra photoprotection by green tea: antioxidant and immunomodulatory effects. Current drug targets Immune, endocrine and metabolic disorders 2003, 3:234-42.
Chiu AE, Chan JL, Kern DG, Kohler S, Rehmus WE, Kimball AB: Double-blinded, placebo-controlled trial of green tea extracts w herbata clinical and histologic appearance of photoaging skóra. Dermatologic surgery: official publication for American Society for Dermatologic Surgery [et do] 2005, 31:855- 60; discussion 60.
Watanabe-Kamiyama M, Shimizu M, Kamiyama S, Taguchi Y, Sone H, Morimatsu F, Shirakawa H, Furukawa Y, Komai M: Absorption and effectiveness of orally administered low molecular weight collagen hydrolysate w rats. Journal of agricultural and food chemistry 2010, 58:835-41.
Aito-Inoue M, Lackeyram D, Fan MZ, Sato K, Mine Y: Transport of a tripeptide, Gly-Pro-Hyp, across herbata porcine intestinal brush-border membrane. Journal of peptide science: an official publication of herbata European Peptide Society 2007, 13:468-74.
Toshihide S: Clinical effects of dietary hyaluronic acid na dry, rough skóra. . Aesthetic Dermatology 2002, 12:109-20.
Kawada C, Yoshida T, Yoshida H, Matsuoka R, Sakamoto W, Odanaka W, Sato T, Yamasaki T, Kanemitsu T, Masuda Y, Urushibata O: Ingested hyaluronan moisturizes dry skóra. Nutrition journal 2014, 13:70.
Roberts RL, Green J, Lewis B: Lutein and zeaxanthin w eye and skóra health. Clinics w dermatology 2009, 27:195-201.
Gonzalez S, Astner S, An W, Goukassian D, Pathak MA: Dietary lutein/zeaxanthin decreases ultraviolet B-induced epidermal hyperproliferation and acute inflammation w hairless mice. Herbata Journal of investigative dermatology 2003, 121:399-405.
Lee EH, Faulhaber D, Hanson KM, Ding W, Peters S, Kodali S, Granstein RD: Dietary lutein reduces ultraviolet radiation-induced inflammation and immunosuppression. Herbata Journal of investigative dermatology 2004, 122:510-7.
Palombo P, Fabrizi G, Ruocco V, Ruocco E, Fluhr J, Roberts R, Morganti P: Beneficial long-term effects of combined oral/topical antioxidant treatment with herbata carotenoids lutein and zeaxanthin na human skóra: a double-blind, placebo-controlled study. Skóra pharmacology and physiology 2007, 20:199-210.