Description
The cream repairing Cicastela è suitable for the skin of the newborn e of the child, a partire dalla nascita for arrossamenti superficiali quotidiani localizzati.
-Promotes un'ottima Repair cutanea.
-Lenisce immediatamente e a lungo.
-Purifica the skin.
-Protects the barrier cutanea e preserva the capitale cellular of the skin.
-91% ingredients of origine natural.
The sua formulation gentle do not brucia quando viene applicata. High tollerabilità cutanea e product Dermatologically tested.
-Perseose of avocado: active natural brevettato, protects the barrier cutanea e preserva the ricchezza cellular of the skin.
-Hyaluronic acid: promotes the Repair cutanea.
-Pantenolo: lenisce fin from subito e a lungo the sensazioni of fastidio.
-Rame-zinc: prevents the rischio of sovra-infezione.

Ingredients
Aqua (Water), caprylic/capric triglyceride, C10-18 triglycerides, panthenol, glycerin, triisostearin, Butyrospermum parkii (Shea) butter, polyglyceryl-3 distearate, Ricinus communis (Castor) seed oil, 1,2-hexanediol, cetearyl alcohol, potassium cetyl phosphate, polyacrylate crosspolymer-6, allantoin, glyceryl caprylate, glyceryl stearate citrate, hydrogenated castor oil, hydrolyzed hyaluronic acid, xanthan gum, copper PCA, zinc PCA, sodium hydroxide, Persea gratissima (Avocado) fruit extract, citric acid.

How to use
Zone of applicazione: contour lips, placche secche, pieghe cutanee, irritazioni from pannolino, escoriazioni, tracce of varicella, bites/stings d'insetto.
The texture "effect barrier" of the cream lascia un film protective do not untuoso. The skin ritrova morbidezza ed Elasticity. L'applicazione of the product è facilitata dal tube a cannula che allows l'utilizzo with precisione.

Storage
Shelf life a packaging unopened: 36 months.
Shelf life after opening: 6 months.

Size
Tube a cannula from 40 ml.

Bibliografia
-Effect of AV119, a natural sugars from avocado, on malassezia furfur invasiveness and on tea expression of HBD-2 and cytokines in human keratinocytes.
Donnarumma J, Buommino E, Baroni A, Auricchio L, De Filippis A, Cozza V, Piccardi N, Msika P, Tufano MA EXPERIMENTAL DERMATOLOGY, 2007; 16(11): 912-9 .
-Patented natural avocado sugars modulate tea HBD-2 expression in human keratinocytes through tea involvement of protein kinase c and protein tyrosine kinases.
Paoletti I, Buommino E, Tudisco L, Baudouin C, Msika P, Tufano MA, Baroni A, Donnarumma G archives of dermatological research, 2010; 302(3): 201-9.
-Functional skin adaptation in infancy - almost complete but not fully competent.
Fluhr JW, Darlenski R, Taieb A, Hachem JP, Baudouin C, Msika P, De Belilovsky C, Berardesca e experimental dermatology, 2010; 19(6): 483-92.
-AV119, a natural sugar from avocado gratissima, modulates tea LPS-induced proinflammatory response in human keratinocytes.
Donnarumma G, Paoletti I, Buommino E, Fusco A, Baudouin C, Msika P, Tufano MA, BaronI A inflammation, 2011; 34 (6): 568-575.
-Adaptation de the peau de the naissance à l'enfance: considérations pratiques.
Fluhr JW, DarlenskI R, Taieb A, Hachem JP, Baudouin C, Msika P, De Belilovsky C, Berardesca E les nouvelles dermatologiques, 2011; 30(4): 229-32.
-Infant epidermal skin-physiology: adaptation after birth.
Fluhr JW, Darlenski R, Lachmann N, Baudouin C, Msika P, De Belilovsky C, Hachem JP British journal of dermatology, 2012; 166(3):483-90.
-Skin physiology adaptation in infants
Fluhr et to the BJD Editor's choice Journal of investigative dermatology, 2012; 132: P132.
-Patented natural avocado sugar modulates tea HBD-2 and HBD-3 expression in human keratinocytes through toll like receptor-2 and erk/mapk activation.
Paoletti I, Buommino E, Fusco A, Baudouin C, Msika P, Tufano MA, Baroni A, Donnarumma G Archives of dermatological research, 2012; 304(8): 619-625.
-Effects of a patented natural sugar on M.Furfur pathogenicity and HBD2 expression.
Buommino E, Donnarumma G, Orlando M, Auricchio L, De Filippis A, Piccardi N, Msika P, Tufano MA Journal of investigative dermatology, august 2006; volume 126, issue S3, page S52, abstract 299.
-Avocado sugars are effective inducer of cutaneous defensive functions Bredif S, Garnier S, Piccardi N and Msika P. Journal of investigative dermatology, april 2007; volume 127, issue S1, page S69, abstract 413.
-Is tea functional skin adaptation complete and competent in infancy?
Fluhr JW, Darlenski R, Hachem JP, Baudouin C, Msika P, De Belilovsky C, Berardesca E. Journal of investigative dermatology, april 2011; volume 131, issue s1, page s46, abstract 274.
-Comparison of tea skin physiology of neonates and young children with that of adults: a randomised clinical trial.
Fluhr JW, Lachmann N, Baudouin C, Williams R, De Belilovsky C, Hachem Jp, Msika P. Journal of investigative dermatology, april 2011; volume 131, issue s1, page s81, abstract 481.
-Skin adaptation from birth to childhood: practical considerations.
Fluhr JW, Darlenski R, Hachem JP, Baudouin C, Msika P, De Belilovsky C, Berardesca E. Journal of tea american academy of dermatology, february 2011; volume 64, issue 2, supplement 1 , page AB136.
-Ability of natural avocado sugars to prevent cutaneous inflammation.
Bredif S, Buommino E, Tufano Ma, Baudouin C, Paoletti I, Garnier S, Baroni A, Msika P. Journal of investigative dermatology, september 2011, volume 131, issue s2, page s9, abstract 054.
-Patented avocado sugars modulate HBD-2 expression in human keratinocytes through toll-like-receptor-2.
Paoletti I, Buommino E, Donnarumma G, Baroni A, Baudouin C, Msika P and Tufano Ma. Journal of investigative dermatology, september 2011, volume 131, issue s2, page s85, abstract 510.
-Skin physiology and surface isotropy investigations in young children of different age groups compared to adults: (E.M.I) score.
Fluhr JW, Baudouin C, De Belilovsky C, Hachem JP, Darlenski R, Lachmann N, Msika P. Journal of tea american academy of dermatology, april 2013, volume 68 (n°4), supplement 1, page ab177, abstract P6883.
-Molecular biomarkers' analysis to characterize epidermis of infants.
Baudouin C, Brédif S, Pedretti N, Barrault C, Bernard FX and Msika P. Journal of investigative dermatology, may 2013; volume 133, issue s1, page s106, abstract 622.
-Avocado perseose, a biomimetic active ingredient for tea protection and accompaniment of infants' skin.
Leclère-Bienfait S, Rocheteau J, Brédif S, Baudouin C, Saunois A and Msika P. Journal of investigative dermatology, may 2013; volume 133, issue s1, page s106, abstract 623.