{"product_id":"mustela-cicastela-40-ml","title":"Mustela Cicastela 40 ml","description":"\u003cp\u003e\u003c\/p\u003e\u003ch1\u003eCICASTELA\u003cbr\u003e REPAIR CREAM\u003c\/h1\u003e \u003cdiv align=\"justify\"\u003e\n\n\u003cb\u003eDescription\u003c\/b\u003e\u003cbr\u003e Cicastela repair cream is suitable for newborn and baby skin, from birth, for daily superficial localized redness. \u003cbr\u003e -Promotes optimal skin repair.\u003cbr\u003e -Soothes immediately and for a long time.\u003cbr\u003e -Purifies the skin.\u003cbr\u003e -Protects the skin barrier and preserves the skin's cellular capital.\u003cbr\u003e -91% ingredients of natural origin.\u003cbr\u003eIts delicate formulation does not sting when applied. High skin tolerability and dermatologically tested product. \u003cbr\u003e -Avocado Perseose: patented natural active ingredient, protects the skin barrier and preserves the skin's cellular richness. \u003cbr\u003e -Hyaluronic acid: promotes skin repair. \u003cbr\u003e -Panthenol: immediately and long-lastingly soothes sensations of discomfort. \u003cbr\u003e -Copper-zinc: prevents the risk of superinfection.\u003cbr\u003e\u003cbr\u003e \u003cb\u003eComponents\u003c\/b\u003e\u003cbr\u003e Aqua (Water), caprylic\/capric triglyceride, C10-18 triglycerides, panthenol, glycerin, triisostearin, Butyrospermum parkii (Shea) butter, polyglyceryl-3 distearate, Ricinus communis (Castor) seed oil, 1,2-hexanediol, cetearyl alcohol, potassium cetyl phosphate, polyacrylate crosspolymer-6, allantoin, glyceryl caprylate, glyceryl stearate citrate, hydrogenated castor oil, hydrolyzed hyaluronic acid, xanthan gum, copper PCA, zinc PCA, sodium hydroxide, Persea gratissima (Avocado) fruit extract, citric acid.\u003cbr\u003e\u003cbr\u003e \u003cb\u003eDirections for use\u003c\/b\u003e\u003cbr\u003e Application areas: lip contour, dry patches, skin folds, diaper rash, excoriations, chickenpox marks, insect bites.\u003cbr\u003eThe \"barrier effect\" texture of the cream leaves a non-greasy protective film. The skin regains softness and elasticity. Product application is facilitated by the cannula tube which allows for precise use.\u003cbr\u003e \u003cbr\u003e \u003cb\u003eStorage\u003c\/b\u003e\u003cbr\u003e Shelf life in unopened package: 36 months.\u003cbr\u003e Shelf life after opening: 6 months.\u003cbr\u003e\u003cbr\u003e \u003cb\u003eFormat\u003c\/b\u003e\u003cbr\u003e 40 ml cannula tube.\u003cbr\u003e\u003cbr\u003e \u003cb\u003eBibliography\u003c\/b\u003e\u003cbr\u003e -Effect of AV119, a natural sugars from avocado, on malassezia furfur invasiveness and on the expression of HBD-2 and cytokines in human keratinocytes. \u003cbr\u003e Donnarumma J, Buommino E, Baroni A, Auricchio L, De Filippis A, Cozza V, Piccardi N, Msika P, Tufano MA EXPERIMENTAL DERMATOLOGY, 2007; 16(11): 912-9 .\u003cbr\u003e -Patented natural avocado sugars modulate the HBD-2 expression in human keratinocytes through the involvement of protein kinase c and protein tyrosine kinases.\u003cbr\u003e Paoletti I, Buommino E, Tudisco L, Baudouin C, Msika P, Tufano MA, Baroni A, Donnarumma G archives of dermatological research, 2010; 302(3): 201-9.\u003cbr\u003e -Functional skin adaptation in infancy - almost complete but not fully competent.\u003cbr\u003e Fluhr JW, Darlenski R, Taieb A, Hachem JP, Baudouin C, Msika P, De Belilovsky C, Berardesca e experimental dermatology, 2010; 19(6): 483-92.\u003cbr\u003e -AV119, a natural sugar from avocado gratissima, modulates the LPS-induced proinflammatory response in human keratinocytes.\u003cbr\u003e Donnarumma G, Paoletti I, Buommino E, Fusco A, Baudouin C, Msika P, Tufano MA, BaronI A inflammation, 2011; 34 (6): 568-575.\u003cbr\u003e -Adaptation de la peau de la naissance à l'enfance: considérations pratiques.\u003cbr\u003e Fluhr JW, DarlenskI R, Taieb A, Hachem JP, Baudouin C, Msika P, De Belilovsky C, Berardesca E les nouvelles dermatologiques, 2011; 30(4): 229-32.\u003cbr\u003e -Infant epidermal skin-physiology: adaptation after birth.\u003cbr\u003e Fluhr JW, Darlenski R, Lachmann N, Baudouin C, Msika P, De Belilovsky C, Hachem JP British journal of dermatology, 2012; 166(3):483-90.\u003cbr\u003e -Skin physiology adaptation in infants\u003cbr\u003e Fluhr et al BJD Editor's choice Journal of investigative dermatology, 2012; 132: P132.\u003cbr\u003e -Patented natural avocado sugar modulates the HBD-2 and HBD-3 expression in human keratinocytes through toll like receptor-2 and erk\/mapk activation.\u003cbr\u003e Paoletti I, Buommino E, Fusco A, Baudouin C, Msika P, Tufano MA, Baroni A, Donnarumma G Archives of dermatological research, 2012; 304(8): 619-625.\u003cbr\u003e -Effects of a patented natural sugar on M.Furfur pathogenicity and HBD2 expression.\u003cbr\u003e Buommino E, Donnarumma G, Orlando M, Auricchio L, De Filippis A, Piccardi N, Msika P, Tufano MA Journal of investigative dermatology, august 2006; volume 126, issue S3, page S52, abstract 299.\u003cbr\u003e -Avocado sugars are effective inducer of cutaneous defensive functions Bredif S, Garnier S, Piccardi N and Msika P. Journal of investigative dermatology, april 2007; volume 127, issue S1, page S69, abstract 413.\u003cbr\u003e -Is the functional skin adaptation complete and competent in infancy?\u003cbr\u003e Fluhr JW, Darlenski R, Hachem JP, Baudouin C, Msika P, De Belilovsky C, Berardesca E. Journal of investigative dermatology, april 2011; volume 131, issue s1, page s46, abstract 274.\u003cbr\u003e -Comparison of the skin physiology of neonates and young children with that of adults: a randomised clinical trial.\u003cbr\u003e Fluhr JW, Lachmann N, Baudouin C, Williams R, De Belilovsky C, Hachem Jp, Msika P. Journal of investigative dermatology, april 2011; volume 131, issue s1, page s81, abstract 481.\u003cbr\u003e -Skin adaptation from birth to childhood: practical considerations.\u003cbr\u003e Fluhr JW, Darlenski R, Hachem JP, Baudouin C, Msika P, De Belilovsky C, Berardesca E. Journal of the american academy of dermatology, february 2011; volume 64, issue 2, supplement 1 , page AB136.\u003cbr\u003e -Ability of natural avocado sugars to prevent cutaneous inflammation.\u003cbr\u003e Bredif S, Buommino E, Tufano Ma, Baudouin C, Paoletti I, Garnier S, Baroni A, Msika P. Journal of investigative dermatology, september 2011, volume 131, issue s2, page s9, abstract 054.\u003cbr\u003e -Patented avocado sugars modulate HBD-2 expression in human keratinocytes through toll-like-receptor-2.\u003cbr\u003e Paoletti I, Buommino E, Donnarumma G, Baroni A, Baudouin C, Msika P and Tufano Ma. Journal of investigative dermatology, september 2011, volume 131, issue s2, page s85, abstract 510.\u003cbr\u003e -Skin physiology and surface isotropy investigations in young children of different age groups compared to adults: (E.M.I) score.\u003cbr\u003e Fluhr JW, Baudouin C, De Belilovsky C, Hachem JP, Darlenski R, Lachmann N, Msika P. Journal of the american academy of dermatology, april 2013, volume 68 (n°4), supplement 1, page ab177, abstract P6883.\u003cbr\u003e -Molecular biomarkers' analysis to characterize epidermis of infants.\u003cbr\u003e Baudouin C, Brédif S, Pedretti N, Barrault C, Bernard FX and Msika P. Journal of investigative dermatology, may 2013; volume 133, issue s1, page s106, abstract 622.\u003cbr\u003e -Avocado perseose, a biomimetic active ingredient for the protection and accompaniment of infants' skin.\u003cbr\u003e Leclère-Bienfait S, Rocheteau J, Brédif S, Baudouin C, Saunois A and Msika P. Journal of investigative dermatology, may 2013; volume 133, issue s1, page s106, abstract 623.\u003cbr\u003e \u003c\/div\u003e","brand":"LAB.EXPANSCIENCE ITALIA SRL","offers":[{"title":"Default Title","offer_id":57340221096280,"sku":"978545236","price":13.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0968\/9301\/0264\/files\/978545236.jpg?v=1779333505","url":"https:\/\/www.globalpharmacy.it\/en\/products\/mustela-cicastela-40-ml","provider":"Global Pharmacy","version":"1.0","type":"link"}