Description
Medical device containing macrogol 4000, an osmotic laxative.
Isypan Constipation has a high capacity to rehydrate and soften hard stools, facilitating their evacuation and providing a feeling of relief.
It has a physical mechanism of action and works gently: it is not absorbed by the body, is eliminated in an unchanged form, and does not produce gas.
It can be taken in cases of occasional bowel irregularity and is particularly indicated for chronic constipation.
It is suitable for children from 2 years old, the elderly, and celiacs.
Its regulating function is promoted by a healthy lifestyle and a proper diet, rich in fiber, fruit, and vegetables, with adequate fluid intake and good physical activity.
It contains no flavorings, sugar, or electrolytes.

Components
Macrogol 4000.
Does not contain electrolytes.
Does not contain excipients or sweeteners, flavorings, or sugars.
Does not contain preservatives.
Does not contain gluten.

Directions for use
Isypan Constipation can be used from 2 years of age.
Isypan Constipation shows its effectiveness 48 hours after administration and can be used for treatments lasting a maximum of 30 days.
Its formulation containing only macrogol 4000 makes it suitable for patients requiring a low-sodium, galactose-free, and gluten-free diet.
It should be diluted with a cold or hot beverage of choice (approx. 150 ml): for example, a glass of water, fruit juice, tea, or even milk, stirring until a homogeneous solution is obtained. The absence of flavorings and sweeteners does not alter the taste of the beverage. Drink the reconstituted solution. The product is for single use; do not use partial or already opened sachets. Do not use the device in a manner other than that indicated by the manufacturer.
- Adults: The appropriate dose is the minimum sufficient to produce regular evacuation of soft stools and must be adapted according to the observed effects. It ranges from 1 sachet every other day (especially for pediatric use) up to 2 sachets per day. When regular defecation is achieved, the dosage should be reduced to 1 sachet per day or every other day. The maximum daily dose can reach 20 g and can be taken in a single administration. Do not exceed the maximum daily dose of 20 g.
- Children: For patients from 2 years of age, the recommended dose is 0.7 g/kg. Up to 20 kg of weight, the dosage should be based on body weight according to the doctor's instructions.

Warnings
Do not take Isypan Constipation in case of hypersensitivity to macrogol 4000 and gastrointestinal perforation and/or obstruction. If in doubt, consult your doctor or pharmacist before taking Isypan Constipation.
As with all laxatives, before starting treatment, organic disorders must be ruled out. Isypan Constipation can be taken for prolonged periods, but if symptoms persist despite associated dietary measures, medical advice is necessary to rule out underlying pathologies.
There are no adequate and well-controlled studies; therefore, do not take Isypan Constipation during pregnancy and/or breastfeeding.
Do not take concomitantly with oral medications.
Excessive doses of Isypan Constipation can cause diarrhea, abdominal pain, abdominal distension, and vomiting, which resolve when treatment is stopped or the dose is reduced. In these circumstances, you should contact your doctor.
Do not take a double dose of Isypan Constipation to make up for a missed dose.
Keep out of reach of children.

Possible side effects observed in adults and children: diarrhea, abdominal pain, abdominal distension, nausea, vomiting, fecal incontinence, and flatulence. Rare cases of allergic reactions; in this case, discontinue use of the product and inform your doctor or pharmacist. In case of diarrhea, which generally disappears when treatment is stopped or the dose is reduced, it may be advisable to contact your doctor. If any of the side effects get worse, or if you notice any side effects not listed in this leaflet, tell your doctor or pharmacist.

Storage
Store the original packaging in a cool, dry place, out of sight and reach of children.
The indicated expiry date refers to the product in intact packaging and correctly stored.
Do not use the product after the expiry date indicated on the package.
Shelf life when unopened: 60 months.

Format
Pack of 20 sachets of 10 g.
Net weight 200 g.

Code 410001529