Astroferrina
            Nasal Douche

CE Medical Device, Class I. Spray for the hygiene of nasal mucous membranes, useful in the presence of breathing difficulties due to pathologies.
Indicated for all chronic catarrhal pathologies of the nose and related structures: rhinitis, rhinosinusitis, rhinopharyngitis, in rhinosinuso-bronchial syndromes. It removes dirt and bacteria from the nasal cavities, significantly reducing the risk of contagion from common colds, cleans the sinus cavities and is an effective treatment for sinusitis, allows for the treatment of post-cold or flu symptoms by removing mucus and phlegm from the upper respiratory tract cavities, is an aid in the treatment of asthma, is also used successfully for ear affections, middle ear inflammations, otitis, etc. It helps to improve olfactory sensitivity and thus regain the sense of smell and partially sharpen taste and improve digestive processes.

Instructions for use
Remove the cap and place the dispenser in the nostril. Nebulize 1 or 2 sprays into the nasal cavity once or more times a day as needed.

Warnings
Before using the product, consult a doctor, especially after surgery on the upper respiratory tract or in cases of bleeding, especially if of unknown etiology. In cases of recognized intolerance to one or more listed ingredients, avoid using the product. It may be normal to feel a slight burning sensation due to the salinity of the solution. Keep out of reach and sight of children. After use, close the dispenser tightly. After use, do not discard the bottle and dispenser in the environment.

Storage
Store at a temperature not exceeding 25°C. The expiration date refers to the product in intact packaging and correctly stored.

Components
Purified water; sodium chloride; preservatives: sodium benzoate and potassium sorbate; citric acid.

Format
Bottle with 100 ml dispenser.

Bibliography
   -    Otolarryngol Pol. 2011 Jan-Feb;65(1):47-53. doi: 10.1016/S0030-6657(11)70627-8. Use of isotonic NaCl solution in patients with acute rhinosinusitis
Jurkiewicz D, Rapiejko P. Auris Nasus Larynx. 2013 Aug 8. pii: S0385-8146(13)00156-9. doi: 10.1016/j.anl.2013.07.008. [Epub ahead of print]
Klinika Otolaryngologii, Wojskowy Instytut Medyczny W Warszawie.
   -    Compliance and efficacy of saline irrigation in pediatric chronic rhinosinusitis. Hong SD, Kim JH, Kim HY, Jang MS, Dhong HJ, Chuna SK. Department of Otorhinolaryngology - Head and Neck Surgery, Samsung Medical Center, Sungkyunkwan University School of Medicine, 50 Irwon-dong, Gangnam-gu, Seoul 135-710, Republic of Korea.
   -    J Fam Pract. 2002 Dec;51(12):1049-55.
Efficacy of daily hypertonic saline nasal irrigation among patients with sinusitis: a randomized controlled trial. Rabago D, Zgierska A, Mundt M, Barrett B, Bobula J, Maberry R. Department of Family Medicine, University of Wisconsin, Madison, 53715, USA.
   -    Dr Blog La medicina in chiaro.
Pediatr Alleray Immunol. 2012 Aug;23 Suppl 22:32-44. doi: 10.111l/j.1399-3038.2012.01322.x. Management of chronic rhinosinusitis.
Cazzavillan A, Castelnuovo P, Berlucchi M, Baiardini I, Franzetti A, Nicolai P, Gallo S, -Passalacqua G. Pediatric ENT Department, Buzzi Children's Hospital, Istituti Clinici di Perfezionamento, Via Castelvetro 32, Milan, Italy.
   -    Cochrane Database Syst Rev. 2007 Jul 18;(3):CD006394.
Nasal saline irrigations for the symptoms of chronic rhinosinusitis.
Harvey R, Hannan SA, Badia L, Scaddina G. Royal National Throat Nose and Ear Hospital, London/John Radcliffe Hospital, Oxford, Otolaryngology, Head & Neck Surgery/Cochrane ENT Disorders Group, Level LGI West Wing, John Radcliffe Hospital, Oxford, UK, OX3 9DU.